Headache is a major reason for acute care and ED visits. Migraine headache, in particular, is a significant cause for intense pain, missed work, and decreased quality of life. In recent years, treatment of migraine has been revolutionized by biologic agents that inhibit calcitonin gene-related peptide (CGRP). Although these drugs were initially only for prophylactic use, usage has expanded to include acute management of headache. In this presentation, methods of acute headache management will be compared with regard to ease of use, efficacy, and cost.
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